Let us for a moment consider an example of our craving for fame. If our mind gives in to the craving, we end up over exerting and tormenting ourselves. This in turn disrupts the chemical composition of our body like glucose, and in the long term it would affect our health (many of our disease are believed to be emanating from stress). The disease in turn would leave our mind pre-occupied with fear, precluding us from focusing on the larger purpose of life. It would also restrict our physical activity owing to the nature of the disease (depending on how debilitating the disease is ).
Hence the Bhagawad Gita endorses the importance of disciplining the mind and the body. Yoga, meditation etc. have proved to restore the balance of energy in our body, and help maintain good health. This combined with the training of mind , to not give in to material desires, by being detached, helps in holistic well being. The mind by being detached, restrains our sense organs, and ensures that we do not indulge in debilitating activities. When the mind and the body are sound, when we are not over whelmed by fear or handicaps of any kind, we are better equipped to be effective.
I would therefore recommend that each of us take up an activity, Yoga, sport anything that helps us maintain a sense of physical well being, in addition to practicing spiritual principles (detachment etc.), to lead an effective life.